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Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases

✍ Scribed by Sakariassen, Kjell S; Alberts, Peteris; Fontana, Pierre; Mann, Jessica; Bounameaux, Henri; Sorensen, Alexandra Santana


Book ID
121195325
Publisher
Future Medicine
Year
2009
Tongue
English
Weight
540 KB
Volume
5
Category
Article
ISSN
1479-6678

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas