A theoretical study is presented of the catalytic mechanism of dihydrofolate reductase (DHFR) enzyme based upon the characterization of the transition structure (TS) for the hydride transfer step. Analytical gradients at AM1 and PM3 semiempirical levels have been used to characterize the saddle poin
Effect of pH on Hydride Transfer by Escherichia coli Dihydrofolate Reductase
β Scribed by Dr. E. Joel Loveridge; Prof. Dr. Rudolf K. Allemann
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 254 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1439-4227
No coin nor oath required. For personal study only.
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