Effect of pH on a gossypol complex with phospholipids: Gossypol-PE
โ Scribed by M. S. Kuk; J. M. Bland
- Book ID
- 107490402
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 144 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0003-021X
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Gossypol (1,1 ',6,6 ',7,7'-hexahydroxy-5,5 ' -diisopropyl-3,3 '-dimethyl[2,2'-binaphthalene]-8,8' dicarboxaldehyde) previously used as a male oral contraceptive is an amphiphilic compound. At low concentrations, it is expected that gossypol would intercalate into the phospholipid bilayers. To demons
## Abstract Our previous studies suggested that combined lowโdose gossypol with steroid hormones possesses a reversible antifertility role on adult male rat. Spermatocyte apoptosis during the meiosis of spermatogenesis is the main reason for the antifertility. This study evaluates the effects of th