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Effect of PGE1 treatment on in vitro thymocyte function of normal and autoimmune mice

✍ Scribed by Judith Whittum-Hudson; Mark Ballow; Robert B. Zurier

Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 598 KB
Volume: 16
Category: Article
ISSN: 0162-3109
DOI: 10.1016/0162-3109(88)90015-x

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## Abstract The __RANKL__/__RANK__/__OPG__ pathway is essential for bone remodeling regulation. Many hormones and cytokines are involved in regulating gene expression in most of the pathway components. Moreover, any deregulation of this pathway can alter bone metabolism, resulting in loss or gain o