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Effect of pepsin inhibitor from Ascaris lumbricoides on cathepsin D and E

✍ Scribed by H. Keilová; V. Tomášek

Book ID
115732859
Publisher
Elsevier Science
Year
1972
Weight
207 KB
Volume
284
Category
Article
ISSN
0005-2744

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Val-D-Leu-Pro-Phe-Phe-Val-D-Leu, a specific inhibitor of aspartate proteinases of the pepsin type, was synthesized. Its bonding to activated 6-aminohexanoic acid-Sepharose 4B afforded an affinity support suitable for the purification of human, porcine, and chicken pepsin, human gastricsin, and bovin