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โœฆ   LIBER   โœฆ

Effect of pentoxifylline, a multidrug resistance reversal agent, on haemopoietic stem cell homing.

โœ Scribed by R.P. Gude; M.P. Chitnis; S.G.A. Rao

Book ID
102563720
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
238 KB
Volume
18
Category
Article
ISSN
1065-6995

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โœฆ Synopsis

ABSTRACT

This paper investigates the mechanism of mouse haemopoietic stem cell homing into the cytoskeleton depolymerising agent Pentoxifylline was used, and shown to inhibit stem cell homing. The inhibition was reversible after 6 hours. The results obtained suggest that the haemopoietic stem cell homing receptor is anchored to cytoskeletal support intracellularly.

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