## Synopsis A quantity, called the linking number, is defined, which specifies the total number of t,wists in a circular helix. The linking number is invariant under continuous deformations of the ring and therefore enables one to calculate the influence of superhelical structures on the secondary
Effect of PbII on the Secondary Structure and Biological Activity of Trypsin
โ Scribed by Lin Yang; Zhiyong Gao; Ying Cao; Ruimin Xing; Xiuying Zhang
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 218 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1439-4227
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## Abstract Recently the peptide Hyโa1 (IFGAILPLALGALKNLIK), with antimicrobial activity, was isolated from the skin secretion of the frog Hypsiboas albopunctatus. The aim of the present work was to evaluate four analogues with introduction of acetyl group, Asp or Lys at the Nโterminus of antimicro