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Effect of pathogenic lipopolysaccharide translocation on human colonic smooth muscle cell contraction

✍ Scribed by M.P.L. Guarino; C. Severi; S. Carotti; G. Ferraguti; A.M. Altomare; R. Alloni; R. Caviglia; S. Emerenziani; M. Cicala

Book ID: 119631887
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 332 KB
Volume: 38
Category: Article
ISSN: 1590-8658
DOI: 10.1016/s1590-8658(06)80083-6

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## Abstract Endotoxemia by bacterial lipopolysaccharide (LPS) has been reported to affect gut motility specifically depending on Toll‐like receptor 4 activation (TLR4). However, the direct impact of LPS ligation to TLR4 on human smooth muscle cells (HSMC) activity still remains to be elucidated. Th