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Effect of parathyroid hormone-related protein in an in vitro hypertrophy model for mesenchymal stem cell chondrogenesis

✍ Scribed by Michael B. Mueller, Maria Fischer, Johannes Zellner…

Book ID
120771326
Publisher
Springer
Year
2013
Tongue
English
Weight
950 KB
Volume
37
Category
Article
ISSN
0341-2695

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## Abstract ## Objective The use of bone marrow–derived mesenchymal stem cells (MSCs) has shown promise in cell‐based cartilage regeneration. A yet‐unsolved problem, however, is the unwanted up‐regulation of markers of hypertrophy, such as alkaline phosphatase (AP) and type X collagen, during in v