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Effect of parathyroid hormone on amino acid transport by cultured neonatal mouse calvarial bone cells

✍ Scribed by John A. Yee

Book ID
112118323
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
674 KB
Volume
3
Category
Article
ISSN
0884-0431

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The involvement of cAMP and calcium in the rise in alkaline phosphatase (AP) activity observed when confluent, serum-free primary cultures of neonatal mouse calvarial cells are treated with parathyroid hormone (PTH) has been studied. Synthetic bovine PTH [bPTH-(1-34)] increased cellular cAMP at conc

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## Abstract Since bone resorption and formation by continuous and intermittent parathyroid hormone (PTH) treatments involve various types of cells in bone, this study examined the underlying mechanism by combining culture systems using mouse primary calvarial osteoblasts and bone marrow cells. The