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Effect of para-aminohippurate on the efflux of valproic acid from the central nervous system of the rabbit

✍ Scribed by Kimberly D.K. Adkison; Karen M. Powers; Alan A. Artru; Danny D. Shen

Book ID
108022891
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
815 KB
Volume
23
Category
Article
ISSN
0920-1211

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✍ Kimberly D.K. Adkison; Alan A. Artru; Karen M. Powers; David Nochlin; Danny D. S πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 615 KB

Previous experiments suggest the primary route of valproic acid (VPA) removal from the rabbit central nervous system (CNS) is by probenecid-sensitive transporters at the blood-brain barrier but not at the choroid plexus. The purpose of this study was to determine if other transport mechanisms at the