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Effect of P2 purinoceptor antagonists on kainate-induced currents in rat cultured neurons

✍ Scribed by Cristina Zona; Caterina Marchetti; Cinzia Volontè; Nicola B. Mercuri; Giorgio Bernardi


Book ID
113995393
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
471 KB
Volume
882
Category
Article
ISSN
0006-8993

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The effects of suramin, reactive blue 2 (RB2) and d-tubocurarine (d-TC) were investigated electrophysiologically to elucidate the mechanisms underlying their antagonism of P2 purinoceptor-mediated responses. All three compounds inhibited an adenosine triphosphate (ATP)-activated inward current in ra