Bone morphogenetic proteins (BMPs) are multifunctional regulators of proliferation, differentiation and apoptosis. BMP-6 is involved in numerous developmental processes. We have demonstrated expression of BMP-6 in breast cancer cell lines by RT-PCR and immuno-histochemistry. The level of BMP-6 mRNA
β¦ LIBER β¦
Effect of over-expression of bone morphogenetic protein-6 on tumour growth in an in vivo model of prostate cancer
β Scribed by B.G. Thomas; T.M. Nilsson; N.J. Brown; J.L. Burton; C.N. Robson; F.C. Hamdy
- Book ID
- 118644396
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 205 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1569-9056
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## Abstract Animal models are important tools to study the development of bone metastases and to evaluate strategies for their prevention and treatment. We here describe a new model in which tumour inoculation is achieved by injection of cancer cells into the femoral artery. This approach results i