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Effect of Organic Isothiocyanates on the P-Glycoprotein- and MRP1-Mediated Transport of Daunomycin and Vinblastine

โœ Scribed by Elaine Tseng; Amrita Kamath; Marilyn E. Morris

Book ID
110395878
Publisher
Springer US
Year
2002
Tongue
English
Weight
187 KB
Volume
19
Category
Article
ISSN
0724-8741

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Effects of benzyl-, phenethyl-, and ฮฑ-naphthyl isothiocyanates on P-glycoprotein- and MRP1-mediated transport
โœ Ke Hu; Marilyn E. Morris ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 203 KB

The objective of this investigation was to evaluate the effects of two dietary isothiocyanates (ITCs), benzyl- (BITC) and phenethyl isothiocyanate (PEITC), and one synthetic ITC, alpha-naphthyl isothiocyanate (1-NITC), on the P-glycoprotein (P-gp)- and multidrug-resistance protein 1 (MRP1)-mediated