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Effect of organic calcium antagonists and magnesium on the development of metrazol kindling

✍ Scribed by G. N. Kryzhanovskii; M. N. Karpova; O. Yu. Pantov

Publisher
Springer US
Year
1990
Tongue
English
Weight
356 KB
Volume
110
Category
Article
ISSN
0007-4888

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A competitive (NBQX) and a non-competitive (GYKI 52466) AMPA antagonist, and a competitive NMDA antagonist (D-CPPene) were tested against the development of kindling and against fully kindled seizures in amygdala-kindled rats. GYKI 52466, 10 mg/kg given i.p. 5 min prior to electrical stimulation in