Effect of oral CDP-choline on plasma choline and uridine levels in humans
โ Scribed by Richard J Wurtman; Meredith Regan; Ismail Ulus; Lilly Yu
- Book ID
- 113992416
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 260 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0006-2952
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Lipid synthesis has been tested in vivo in different brain areas of 12-month-old male rats. Cortex, striatum, brainstem, and subcortex of brain have been examined. The cerebellum was discarded. Mixtures of (2-'HH)glycerol and (Me-''C)choline were injected into the lateral ventricle of the brain as l
## Abstract Recent reports suggest that oral choline supplement may alter the cerebral choline/creatine (Cho/Cr) ratio and might be used to treat neurodegenerative disorders of cholinergic transmission. Using both ^1^H and ^31^P MRS, we reexamined the Cho/Cr ratio and quantified cerebral choline an