Quantification of quinolinic acid in rat
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Melvyn P. Heyes; Sanford P. Markey
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Article
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1988
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Elsevier Science
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English
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A gas chromatography/mass spectrometry assay is described to quantify the endogenous neurotoxin quinolinic acid (QUIN) in brain, whole blood, and plasma. High specificity and high sensitivity were obtained by using negative chemical ionization and accuracy was achieved by using ['80]QUlN as internal