Effect of oestrogen replacement on bone metabolism and cytokines in surgical menopause
β Scribed by F. P. Cantatore; G. Loverro; A. M. Ingrosso; R. Lacanna; E. Sassanelli; L. Selvaggi; M. Carrozzo
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 310 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0770-3198
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A 3-year follow-up study was performed of bone metabolism and bone changes induced by surgical menopause as a consequence of hysterectomy and oophorectomy (OVX) is 52 nonmenopausal women. We investigated 22 bone parameters and determined seven bone indices as indicators of bone mineral content by du
The mechanism by which oestrogen and hormone replacement therapy (HRT) maintain bone mass in women is still unclear. It has previously been shown that cells of osteoblast lineage in vivo, particularly osteocytes, express oestrogen receptor (ER ). Nevertheless, it is still debatable whether oestrogen