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Effect of octreotide on total effective vascular compliance in patients with posthepatitic cirrhosis

✍ Scribed by Han-Chieh Lin; Yang-Te Tsai; May C.-M. Yang; Fa-Yauh Lee; Ming-Chih Hou; Ling-Sheng Chen; Shou-Dong Lee

Book ID
118567372
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
763 KB
Volume
24
Category
Article
ISSN
0168-8278

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Cardiovascular effects of octreotide in
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Octreotide is thought to reduce splanchnic and variceal blood flow with minimal effects on the systemic circulation in cirrhotic patients with portal hypertension. However, we noticed significant bradycardia in some patients immediately after administration of bolus doses of octreotide. Therefore, w

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Although arterial vasodilation is a well-known feature in patients with cirrhosis, the venous system remains unexplored. To measure total effective vascular compliance, a reflection of the properties of the venous system, rapid volume expansion (300 ml of a gelatin solution in 3 min) was performed i