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Effect of obesity on P2X2 receptor and chemical coding in myenteric neurons of males and females mice (ob/ob)

โœ Scribed by M.S. Mizuno; L.A. Velloso; P. Castelucci

Book ID
116267873
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
60 KB
Volume
163
Category
Article
ISSN
1566-0702

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Effect of metformin on hepatocyte insuli
Effect of metformin on hepatocyte insulin receptor binding in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice
โœ J. M. Lord; T. W. Atkins; C. J. Bailey ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 575 KB

The effect of metformin on hepatocyte insulin receptor binding was examined in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice. In normal mice, chronic administration of metformin (60 mg X kg-1 X day-1 for 50 weeks) increased the number of low affinity receptors by 148%.