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Effect of OATP1B Transporter Inhibition on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

โœ Scribed by Lau, Y Y; Huang, Y; Frassetto, L; Benet, L Z


Book ID
110019924
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
259 KB
Volume
81
Category
Article
ISSN
0009-9236

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Effect of milk on the pharmacokinetics o
โœ Kaori Morimoto; Kozue Kishimura; Takaaki Nagami; Nao Kodama; Yoichiro Ogama; Mid ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 240 KB ๐Ÿ‘ 1 views

We previously showed that oseltamivir, a prodrug of the influenza virus neuraminidase inhibitor Ro 64-0802, is a substrate of proton-coupled oligopeptide transporter (PEPT1), and its intestinal absorption in rats is markedly inhibited by administration with milk. To investigate the importance of PEP