๐”– Bobbio Scriptorium
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Effect of nonionic surfactant on bactericidal activity of cetylpyridinium chloride

โœ Scribed by J. W. Bradshaw; C. T. Rhodes; G. Richardson

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
230 KB
Volume
61
Category
Article
ISSN
0022-3549

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โœฆ Synopsis

The interaction of cetylpyridinium chloride with a nonionic surfactant was examined by equilibrium dialysis; and by using the simple aqueous phase saturation model, the effect of the surfactant upon the biological activity of the bactericide was predicted. Determination of the degree of reduction of bactericidal activity showed good agreement with the predicted result over a concentration range of 1&100 p.p.m. of bactericide. Below a concentration of I0 p.p.m., a discrepancy between the predicted and experimental results was possible.

Key phrases

Cetylpyridinium chloride-effect of polysorbate 80 on bactericidal activity against Escherichia coli 0 Polysorbate 8&effect on bactericidal activity of cetylpyridinium chloride against Escherichia coli 0 Formulation, pharmaceuticals-polysorbate 8Ckcetylpyridinium chloride interaction, effect on bactericidal activity

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