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Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugs

✍ Scribed by Ricchi, P; Matola, T Di; Ruggiero, G; Zanzi, D; Apicella, A; di Palma, A; Pensabene, M; Pignata, S; Zarrilli, R; Acquaviva, A M


Book ID
109997246
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
165 KB
Volume
86
Category
Article
ISSN
0007-0920

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Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit proliferation and angiogenesis in colorectal cancer. We examined a possible involvement of store-operated calcium (SOC) entry in human colon carcinoma cells (HRT-18), which require calcium for proliferation. Acetyl-salicylic-acid (ASA), mefenami