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Effect of NMDA antagonists on the death of cerebellar granule neurons at different ages

✍ Scribed by Silvestre Alavez; Sugela Blancas; Julio Morán


Book ID
116768452
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
239 KB
Volume
398
Category
Article
ISSN
0304-3940

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## Abstract Palytoxin (PTX) is a potent marine phycotoxin that binds to the Na,K‐ATPase, converting this pump into an open channel. We have recently shown (Vale et al., 2006) that PTX causes an irreversible increase in the cytosolic calcium concentration ([Ca^2+^]~c~) in primary cultures of cerebel