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Effect of nifedipine on carbohydrate metabolism in the rat

✍ Scribed by W. H. Hörl; M. Haag; W. Riegel; A. Heidland


Publisher
Springer
Year
1987
Tongue
English
Weight
596 KB
Volume
187
Category
Article
ISSN
0372-8722

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✍ JOHN S. GRUNDY; LISE A. ELIOT; ROBERT T. FOSTER 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB 👁 2 views

The peroral (po) bioavailability of nifedipine is reported to range from about 45 to 58% in the rat; this compares favourably to human beings. The metabolism of nifedipine is similar in rats and humans (oxidation of the dihydropyridine ring), with the liver believed to be solely responsible for the