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Effect of nifedipine monotherapy on platelet aggregation in patients with untreated essential hypertension

✍ Scribed by Z. Ośmiałowska; M. Nartowicz-Słoniewska; J. M. Słmiński; B. Krupa-Wojciechowska

Publisher
Springer
Year
1990
Tongue
English
Weight
224 KB
Volume
39
Category
Article
ISSN
0031-6970

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✦ Synopsis

The effect of 6 weeks of nifedipine 30-60 mg/d on platelet aggregation and lipid parameters has been studied. A diminution in ADP-, adrenaline- and collagen-induced aggregation was observed. In the case of adrenaline- and collagen-stimulated aggregation the decrease was statistically significant. It was found that platelets which aggregated markedly during the placebo treatment were most strongly inhibited by nifedipine. The changes in lipid parameters were not significantly correlated with changes in aggregation.

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