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Effect of Nicotine Treatment on the Metabolism of Nicotine in the Mouse Liver in Vitro

✍ Scribed by Stålhandske, Torbjörn ;Slanina, Premysl


Book ID
114798635
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
321 KB
Volume
28
Category
Article
ISSN
0001-6683

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The effect of chronic nicotine treatment
✍ Lucinda L. Miner; Allan C. Collins 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 463 KB

Tolerance to nicotine occurs in mice after its chronic administration. This tolerance is accompanied by an up-regulation of nicotinic receptors as assessed by the binding of (3H)-nicotine and alpha-(125I)-bungarotoxin (BTX). Past studies (Marks et al. 1983, 1986) have shown that the increase in BTX