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Effect of nicotine pretreatment on nicotine-induced seizures

✍ Scribed by Lucinda L. Miner; Allan C. Collins


Book ID
113221672
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
570 KB
Volume
29
Category
Article
ISSN
0091-3057

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The effect of chronic nicotine treatment
✍ Lucinda L. Miner; Allan C. Collins πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 463 KB

Tolerance to nicotine occurs in mice after its chronic administration. This tolerance is accompanied by an up-regulation of nicotinic receptors as assessed by the binding of (3H)-nicotine and alpha-(125I)-bungarotoxin (BTX). Past studies (Marks et al. 1983, 1986) have shown that the increase in BTX