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Effect of nelfinavir on insulin metabolism, proteasome activity and protein degradation in HepG2 cells

✍ Scribed by F. G. Hamel; J. Fawcett; B. T. Tsui; R. G. Bennett; W. C. Duckworth

Book ID
109044328
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
147 KB
Volume
8
Category
Article
ISSN
1462-8902

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## Abstract Tumor necrosis factor‐α (TNF‐α) mediated attenuation of insulin signaling pathway is an important cause in several disorders like obesity, obesity linked diabetes mellitus. TNF‐α actions vary depending upon concentration and time of exposure in various cells. In the present study, the e