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Effect of natural and synthetic glucocorticoids on rat hepatic microsomal drug metabolism

✍ Scribed by J.Michael Tredger; Jagadish Chakraborty; Dennis V. Parke

Book ID
116000450
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
703 KB
Volume
7
Category
Article
ISSN
0022-4731

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In Dutch-belted rabbits, pregnancy caused several-fold decrease of in vitro hepatic microsomal aminopyrine, benzphetamine, and hexobarbital biotransformations. In pregnant Sprague-Dawley rats, various kinds of expressing the in vitro rates of hexobarbital biotransformation (per mg of microsomal prot