The effect of ursodeoxycholic acid analogues bearing modifications at the side-chain moiety of the molecule was tested on cholesterol 7a-hydroxylase and HMG-CoA reductase in rat liver microsomes. The compounds included 23R,S mixture and the single isomers 23R and 23S of 23 methylursodeoxycholic acid
Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes
โ Scribed by M. Crestani; E. De Fabiani; B. Malavasi; M. Cancellieri; G. Galli; E. Bosisio
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 568 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0009-3084
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