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Effect of naloxone-precipitated morphine withdrawal on CRH and vasopressin mRNA expression in the rat hypothalamic paraventricular nucleus

✍ Scribed by M.V. Milanés; M.L. Laorden; E. Angel; P. Tankosic; A. Burlet


Book ID
117473265
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
375 KB
Volume
334
Category
Article
ISSN
0304-3940

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In this study, the effect of l-dopa and bromocriptine on morphine withdrawal syndrome was compared. Both l-dopa (125, 250 mg/kg, i.p.) and low doses of bromocriptine (0.04, 0.08 mg/kg, i.p.) potentiated naloxone-induced morphine withdrawal symptoms such as jumping, climbing and rearing in mice. High