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Effect Of N-Acetylcysteine on Carboplatin-Induced Ototoxicity and Nitric Oxide Levels in a Rat Model

✍ Scribed by Erdogan Okur; Metin Kilinc; Ilhami Yildirim; M Akif Kilic; Fatma Inanc Tolun

Book ID
110089016
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
355 KB
Volume
117
Category
Article
ISSN
0023-852X

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## Abstract We investigated whether __N__‐acetylcysteine (NAC), a precursor of glutathione, could protect rabbit articular chondrocytes against nitric oxide (NO)‐induced apoptosis and could prevent cartilage destruction in an experimental model of osteoarthritis (OA) in rats. Isolated chondrocytes