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Effect of mutations in the upstream promoter on the transcription of human 5S rRNA genes

โœ Scribed by Charlotte Hallenberg; Sune Frederiksen

Book ID
114147389
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
415 KB
Volume
1520
Category
Article
ISSN
0167-4781

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The 25S rRNA gene of Saccharomyces cerevisiae is preceded by a bona fide TATA sequence which allows the initiation of transcription--presumably by polymerase II--from the same strand as the 25S rRNA gene. When the promoter fragment is cloned in front of a lacZ gene equipped with an initiation codon