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Effect of molecular therapeutics on liver regeneration in a murine model

✍ Scribed by George Van Buren II; Anthony D. Yang; Nikolaos A. Dallas; Michael J. Gray; Sherry J. Lim; Ling Xia; Fan Fan; Yan Wu; Daniel J. Hicklin; Lee M. Ellis

Book ID
113678113
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
36 KB
Volume
205
Category
Article
ISSN
1072-7515

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Hepatocellular carcinoma (HCC) is a common cause of cancer-related death. Sorafenib prolongs survival of patients with advanced disease and is approved for the systemic treatment of unresectable HCC. It possesses antiangiogenic and antiproliferative properties by way of inhibition of the receptor ty