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Effect of Model Selection on Prediction of Periodic Behavior in Gene Regulatory Networks

✍ Scribed by Tomáš Gedeon, Graham Cummins, Jeffrey J. Heys


Book ID
113085135
Publisher
Springer
Year
2012
Tongue
English
Weight
910 KB
Volume
74
Category
Article
ISSN
1522-9602

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In this paper, we consider the existence conditions of periodic oscillations in large-scale cyclic gene regulatory networks. Using the Poincaré-Bendixson theorem for cyclic systems, we first show that the local instability of an equilibrium point implies the existence of periodic oscillations. We th