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Effect of MK-886 on Ca2+ Level and Viability in PC3 Human Prostate Cancer Cells

✍ Scribed by Jong-Khing Huang; Chorng-Chih Huang; Ti Lu; Hong-Tai Chang; Ko-Long Lin; Jeng-Yu Tsai; Wei-Chuan Liao; Jau-Min Chien; Chung-Ren Jan

Book ID
111316663
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
315 KB
Volume
104
Category
Article
ISSN
1742-7835

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## Abstract The present study evaluated the effects of thimerosal, a vaccine preservative, on cytosolic free Ca^2+^ concentrations ([Ca^2+^]~i~) in human prostate cancer cells (PC3). Thimerosal (10–200 ¡M) increased [Ca^2+^]~i~ in a concentration‐dependent manner. The Ca^2+^ signal was reduced part