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Effect of methionine on hepatotoxicity due to co-administration of gentamicin and indomethacin in rats

โœ Scribed by Amin Derakhshanfar, Zohreh Mojdeganlou, Mahdi Hashempour Sadeghian


Book ID
118787989
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
217 KB
Volume
21
Category
Article
ISSN
1618-5641

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The intraperitoneal administration of gentamicin (100 mg kg[-1] day[-1]) to rats is associated with an increased production of malondialdehyde (MDA), which is an end product of lipid peroxidation in the kidney. The level of glutathione (GSH) and the activity of three antioxidant systems--superoxide