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Effect of methamphetamine on the pharmacokinetics of dextromethorphan and midazolam in rats

✍ Scribed by M. Dostalek; E. Hadasova; M. Hanesova; J. Pistovcakova; A. Sulcova; J. Jurica; J. Tomandl; I. Linhart

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
783 KB
Volume
30
Category
Article
ISSN
0378-7966

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Forty-eight male Wistar rats were exposed to contingent light-shock combinations and 48 rats received light and shock stimuli in a random order. One day after fear conditioning the animals were tested for startle potentiation after injection of midazolam (0, 0.5, 1.0, 2.0 mg/kg, IP) or DMCM (methyl-