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Effect of melatonin on the induction of foci of aberrant crypts in the colon by azoxymethane in rats

✍ Scribed by John H. Weisburger; Abraham Rivenson; Chang-In Choi; Joel Reinhardt; Brian Pittman; Edith Zang

Book ID
105646335
Publisher
Japan Science and Technology Information Aggregator, Electronic
Year
2004
Tongue
English
Weight
144 KB
Volume
9
Category
Article
ISSN
1342-078X

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## Abstract The role of aberrant crypt foci (ACF) as preneoplastic lesions in colon carcinogenesis is not clear. In __Min__/+ mice and their wild‐type littermates treated with azoxymethane (AOM), we previously identified a subgroup of flat ACF that seem more immediate precursors of tumors than the