Effect of medication on biomechanical properties of rabbit bones: Heparin induced osteoporosis
β Scribed by N. Akkas; Y. N. Yeni; B. Turan; E. Delilbasi; U. Gunel
- Book ID
- 105511941
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 836 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0770-3198
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Periprosthetic osteolysis and aseptic loosening of total joint replacements are believed to be initiated often by abnormal bone resorption induced by prosthetic wear debris. Bisphosphonates can inhibit bone resorption and have been successfully used clinically to treat osteoporosis and Paget's disea
The effects of various preservation techniques on the biomechanical properties of bone have been investigated in a rat model. Freezing of the specimens to -20Β°C, -7O"C, and -196Β°C did not adversely affect the strength of long bones tested in torsion or of vertebral bodies tested in compression. Free