## Abstract Individuals with Parkinson's disease show dramatic improvements in their ability to move when medicated. However, the neural cause of this improvement is unclear. One hypothesis is that neural activation patterns, as measured by surface electromyography (EMG), are normalized by medicati
Effect of medication in Parkinson’s disease: a wavelet analysis of EMG signals
✍ Scribed by Soo-kyung Strambi; Bruno Rossi; Gennaro De Michele; Stefano Sello
- Book ID
- 104048721
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 768 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1350-4533
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✦ Synopsis
The improvements in the motor ability in patients with Parkinson's disease due to antiparkinsonian medication is well-known and widely documented. Recent results, based both on kinematic parameters and standard electromyographic (EMG) signal analysis, clearly indicated that the medication reduced, as expected, the clinical signs of Parkinson's disease, but did not restore agonist burst duration modulation with distance in elbow flexion movements. The main aim of the present work is to shed more light on this medication effect using a wavelet analysis approach on multiple EMG signals recorded both on shoulder and elbow muscles in ballistic or rapid movements. The wavelet cross-correlation information allows us to evidence some important quantitative features of the EMG signals due to medication.
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## Abstract We examined the effects of high‐frequency deep brain stimulation of the subthalamic nucleus (STN‐DBS) on characteristics of electromyographic (EMG) activity of the agonist muscle in 8 patients with Parkinson's disease (PD). Patients were examined during STN‐DBS (ON), and 30 minutes afte