Ursodeoxycholic acid (UDCA) induces bicarbonate-rich hypercholeresis by incompletely defined mechanisms that involve the stimulation of adenosine triphosphate (ATP) release from cholangiocytes. As nitric oxide (NO) at a low concentration can stimulate a variety of secretory processes, we investigate
Effect of maternal cholestasis and treatment with ursodeoxycholic acid on the expression of genes involved in the secretion of biliary lipids by the neonatal rat liver
β Scribed by R.I.R. Macias; S. Jimenez; M.A. Serrano; M.J. Monte; J.J.G. Marin
- Book ID
- 116718718
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 322 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0024-3205
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Effect of ursodeoxycholic acid (UDCA) treatment on the expression and function of intestinal multidrug resistance-associated protein (Mrp) 2 was examined in rats. When rats were orally administered 0.5% UDCA solution for 6 days, mRNA and protein levels of Mrp2 in the intestine were increased about t