Effects of the diuretics mannitol or ace
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Nahed M. Osman; Marion P. Copley; Charles L. Litterst
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Article
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1984
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Springer
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English
โ 584 KB
The anticancer drug cisplatin has been known to produce severe renal lesions characterized by high levels of blood urea nitrogen (BUN), toxic nephrosis, and platinum (Pt) retention in the kidney. The effect of IV pretreatment with acetazolamide (ACZ) 30 min before or mannitol (MAN) immediately prior