Effect of malnutrition on susceptibility of mice toTrypanosoma musculi: Vitamin A-deficiency

✍ Scribed by Clarence M. Lee; Georgiana F. Aboko-Cole; John Fletcher

• Book ID: 104776997
• Publisher: Springer-Verlag
• Year: 1976
• Tongue: English
• Weight: 637 KB
• Volume: 49
• Category: Article
• ISSN: 1432-1955
• DOI: 10.1007/bf00445013

✦ Synopsis

Vitamin A-deficiency was studied in mice infected with Trypanosoma musculi. Irrespective of diet, trypomastigotes (trypanosomes) appeared in peripheral tail blood of all inoculated mice after 6-day incubation periods. On the average, vitamin A-deficient mice had parasitemias about 10 times greater than animals fed a complete diet and 8 times pair-fed controls. Parasitemias lasted longer in vitamin-deficient hosts, and reached a maximum five days later than those from control hosts.