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Effect of Macromolecular Crowding on Protein Binding Stability: Modest Stabilization and Significant Biological Consequences

โœ Scribed by Batra, Jyotica; Xu, Ke; Qin, Sanbo; Zhou, Huan-Xiang

Book ID
119205783
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
518 KB
Volume
97
Category
Article
ISSN
0006-3495

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## Abstract In cells, proteins execute specific tasks in crowded environments; these environments influence their stability and dynamics. Similarly, for an enzyme molecule encapsulated in an inorganic cavity as in biosensors or biocatalysts, confinement or excluded volume plays an important role in