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Effect of long-term culture of mouse embryonic stem cells under low oxygen concentration as well as on glycosaminoglycan hyaluronan on cell proliferation and differentiation

✍ Scribed by M. Á. Ramírez; E. Pericuesta; M. Yáñez-Mó; A. Palasz; A. Gutiérrez-Adán

Book ID: 108678021
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 713 KB
Volume: 44
Category: Article
ISSN: 0960-7722
DOI: 10.1111/j.1365-2184.2010.00732.x

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## Abstract This study examined the synergistic effect of high glucose levels and ANG II on proliferation and its related signal pathways using mouse embryonic stem (ES) cells. The combined use of a high glucose concentration (25 mM) and ANG II increased the level of [^3^H]thymidine/BrdU incorporat