## Abstract This study was to determine the efficacy of recombinant human bone morphogenetic protienβ2 (rhBMPβ2)/calcium phosphate matrix (CPX) paste to accelerate healing in a canine articular fracture model with associated subchondral defect. rhBMPβ2/CPX (BMP), CPX alone (CPX) or autogenous bone
Effect of loading and fracture motions on diaphyseal tibial fractures
β Scribed by Augusto Sarmiento; Harry A. McKellop; Adolfo Llinas; Sang-Hyun Park; Bin Lu; William Stetson; Raj Rao
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 535 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0736-0266
No coin nor oath required. For personal study only.
β¦ Synopsis
A computerized motion sensor was used to record the three-dimensional components of interfragmentary motion during healing in three patients with closed, low-energy fractures of the tibial diaphysis treated with functional braces. At the first measurement session 2 weeks after fracture, the patients applied approximately 15 kg to the injured limb. Although this produced 1-4 mm of translation of the fragments, this was recovered when the load was removed. The maximum rotational and angulatory displacements often occurred as the patients rose from the chair with no weight applied to the limb and frequently were reduced as the 15 kg of load was applied. Under load, the maximum axial rotation was 3 degrees and the maximum angular displacement was 1 degree. As with the translations, the initial rotational and angulatory positions of the fragments were recovered when the load was removed and the patient returned to the seated position. At 8 weeks, the patient applied full body weight, producing a maximum interfragmentary translation of 0.5 mm and maximum axial rotation or angulation of 0.5 degrees. Abundant peripheral callus formed in all three fractures, and they healed by 15 weeks through typical gradual consolidation and mineralization of the callus, accompanied by a corresponding reduction in interfragmentary motions.
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One common concern with the manual testing of chevron notched specimens to determine fracture toughness is that it does not provide for precise control over the loading rate. This study examines the effect of loading rate on the measured fracture toughness of 20 identical hardened AISI 4140 steel sa