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Effect of Lipophilicity on Microneedle-Mediated Iontophoretic Transdermal Delivery Across Human Skin In Vitro

โœ Scribed by Pawar, Kasturi R.; Smith, Forrest; Kolli, Chandra Sekhar; Babu, R. Jayachandra

Book ID
121185047
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
659 KB
Volume
102
Category
Article
ISSN
0022-3549

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The use of the isolated perfused porcine skin flap (IPPSF), an alternative in vitro animal model, to predict the profile of the concentration of arbutamine in plasma samples from humans after transdermal iontophoretic administration of this novel catecholamine is described. The strategy involved adm