Effect of linkage status of affected sib-pairs on the search for novel type 1 diabetes susceptibility genes in the HLA complex

Affected sib-pair analysis of the GLUT1

Affected sib-pair analysis of the GLUT1 glucose transporter gene locus in non-insulin-dependent diabetes mellitus (NIDDM): evidence for no linkage

✍ Marco G. Baroni; Juan C. Alcolado; Claudia Gragnoli; Anna M. Franciosi; M. Gisel 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 622 KB

Despite the strong evidence for a major role played by genetic factors in the aetiology of non-insulindependent diabetes mellitus (NIDDM), the genes involved are still unknown. Association studies of candidate genes for the inheritance of NIDDM have so far yielded inconclusive results. Some evidence